E-64蛋白酶抑制剂使用方法

                  E-64蛋白酶抑制剂
编号
品名
规格
说明书
北京华越洋生物04568
张哲源
E-64蛋白酶抑制剂
5mg
北京华越洋生物04569QB
E-64蛋白酶抑制剂
25mg
北京华越洋生物04570TB
  E-64蛋白酶抑制剂溶液
20mg/ml20ml
刘智仁
E-64 蛋白酶抑制剂
基本信息
E-64蛋白酶抑制剂名: trans-Epoxysuccinyl-L-leucylamido(4-guanidino)butane;N-(trans-Epoxysuccinyl)-L-leucine 4-guanidinobutylamide
  E-64蛋白酶抑制剂产品名称: N-( 反式 - 是立党为公、执政为民的根本要求环氧丁二酰基 )-L- 亮氨酸 -4- 胍基丁基酰胺
分子式:伯乐就是你自己阅读答案 C15H27N5O5
分子量: 357.41
CAS 登录号: 66701-25-5
  E-64蛋白酶抑制剂产品描述:
Preparation Note美联储第二次加息 
E-64 is soluble in water. A 20 mg/ml solution can be prepared in water (heat may be needed). A suggested stock solution is a 1 mM aqueous solution. The effective concentration for use as a protease inhibitor is 1 to10 μM. Aqueous stock solutions are stable for months at -20 °C. Diluted solutions are stable for days at neutral pH. E-64 is stable from pH 2-10, but is unstable in ammonia or in HCl. E-64 is also soluble in DMSO, a 10 mM solution can be prepared in dry DMSO and stored at -20 °C. Subsequent dilutions were in culture medium. Solutions for injection were prepared by dissolving E-64 in 0.9% sodium chloride or in a minimum amount of saturated sodium bicarbonate followe
d by dilution with 0.9% sodium chloride (after adjusting the pH to 7.0 with acetic acid).
  E-64蛋白酶抑制剂Biochem/physiol Actions 染料敏化太阳能电池
E-64 is an irreversible, potent, and highly selective cysteine protease inhibitor. E-64 does not react with the functional thiol group of non-protease enzymes, such as L-lactate dehydrogenase or creatine kinase. E-64 will not inhibit serine proteases (except trypsin) like other cysteine protease inhibitors, leupeptin and antipain. The trans-epoxysuccinyl group (active moiety) of E-64 irreversibly binds to an active thiol group in many cysteine proteases, such as papain, actinidase, and cathepsins B, H, and L to form a thioether linkage. E-64 is a very useful cysteine protease inhibitor for use in in vivo studies because it has a specific inhibition, it is permeable in cells and tissues and has low toxicity.
Solubility: H 2 O: soluble1 mM (Stock Solutions stable for months at –20° C.)

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