Drug Dynamics and Pharmacokinetics (DDAP)
I. Definition
镶嵌图形测验
Drug Dynamics and Pharmacokinetics (DDAP) is the study of the changes in the amount and form of drug in the body and the relationship between these changes and the body’s physiological and pharmacological responses.
II. Objectives
The main objective of DDAP is to predict the pharmacological activity and the therapeutic outcome of a drug by understanding the interrelationships between the drug’s pharmacokinetic and pharmacodynamic properties.
III. Topics
纯化水微生物
限度 A. Drug Absorption The process of absorption of drugs into the body from the dosage form is studied in this topic. Factors affecting drug absorption such as routes of administration, the pH of the drug, drug solubility and dissolution rates, membrane permeability, and drug binding are also discussed.穿透科技
B. Drug Distribution
cg时代 This topic deals with the movement of drugs in the body from the site of absorption to their site of action. Factors such as blood flow, protein binding, tissue and organ function, and metabolite formation are discussed.
C. Drug Metabolism
Drug metabolism is the process by which drugs are broken down in the body by enzymes in the blood or tissue. This topic covers the various pathways of drug metabolism, the enzymes involved, how the enzymes are induced or inhibited, and the factors affecting drug metabolism.
D. Drug Excretion
Drug excretion is the process by which the body eliminates drugs from the body. This topic covers the types of drug excretion, the mechanisms of excretion, and the factors that influence the rate of drug elimination.
E. Pharmacokinetics
This topic covers the various aspects of pharmacokinetics including drug absorption, distribution, metabolism, and excretion as well as the mathematical modeling of the processes.奥林匹克大逆转
F. Pharmacodynamics
This topic covers the pharmacological effects of drugs on the body and the mechanisms of action. Factors such as drug receptors, pharmacological action, and drug toxicity are discussed.
IV. Uses
DDAP is used to predict and evaluate the pharmacokinetic and pharmacodynamic behavior of a drug and to design dosage regimens and drug delivery devices. It is also used to develop new drugs by understanding the relationship between drug properties and their pharmacological effects.。
豫公网安备41160202000603
站长QQ:729038198
关于我们
投诉建议