第33卷第1期
2020年2月华夏医学Acta Medicinae Sinica
Vol.33No.1Feb.2020
DOI :10.19296/j.cnki.1008-2409.2020-01-002
CD +
3、CD +
郑梓坤①,谢舒颖,陈为铠,郑拮兰,黄娴婉新感觉f5
(汕头市第三人民医院内四科,广东汕头
515073)
摘要:目的:探讨CD +
3、
CD +
4细胞亚与细胞因子IL-17水平在活动性转归中的诊断价值。方法:选取活动性患者60例设为实验组,前和6个月后检测患者CD + 3、CD +4细胞亚
及IL-17细胞因子,并对患者行痰菌检测,记录痰结核杆菌转阴率;选取同期体检健康者40例设为对照组,
检测其CD +
3、CD +
4与IL-17指标。对两组检测结果进行比较分析。结果:实验组患者外周血中CD +
3、CD +
上运动神经元
4、IL-17水平在前均明显低于对照组(P <0.05);6个月后,实验组患者外周血中CD +
3、CD +
4、IL-17水平高于对照组(P <0.05)。实验组患者中,6个月后有46例患者痰结核杆菌转阴(转归组),
14例患者痰结核杆菌未转阴(未转归组);在前,转归组患者外周血中CD +
3、CD +
4、IL-17水平高于未转归组,但差异无统计学意义(P >0.05);6个月后,转归组患者外周血中CD +3、CD +4、IL-17水平明显高于未转归组(P <0.05);实验组中患者CD +3、CD +4、
IL-17水平与其预后相关(P <0.05)。结论:CD +
3、CD +4细胞亚与细胞因子IL-单摆回复力
17水平动态变化可以显示患者免疫功能,可用于判断和了解活动性患者病情的变化,
评估其预后。关键词:;CD +
海上巨眼
建成区面积3细胞亚;CD +
4细胞亚;IL-17细胞因子中图分类号:R521
文献标志码:A
文章编号:1008-2409(2020)01-0007-04
The diagnostic value of CD 3+、CD 4+subsets and cytokine il-17levels in the course of active pulmonary tuberculosis treatment /ZHENG Zikun ①,XIE Shuying ,CHEN Weikai ,et al ∥The Fourth Internal Medicine ,Shantou Third People ’波斯人
s Hospital ,Shantou 515073,China Abstract :Objective :To investigate the diagnostic value of CD +3、CD +4subsets and cytokine il-17levels in the course of active pulmonary tuberculosis treatment.Methods :60patients diagnosed with active tuberculosis were selected as the experimental group.CD +3、CD +4subsets and il-17cytokines of patients were tested before and 6months after treatment.Meanwhile ,sputum bacteria test was conducted on the experimental group ,
and the sputum tuberculosis bacillus negative conversion rate was recorded.40healthy person wer
e selected as the control group ,and their indicators of CD +3、CD +4and il-17were tested.The results of two groups were compared and analyzed.Results :The levels of CD +3、CD +4and il-17in peripheral blood of the experimental group were significantly lower than those in the control group before treatment
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7·①
作者简介:郑梓坤(1981-),男,广东汕头人,2008年南方医科大学临床医学专业本科毕业,学士学位,现任汕头市第三人民医
院内四科主治医师。研究方向:及其他传染病诊治。