第19卷第1期Vol.19No.1
2013年1月January.2013
Guiding Journal of Traditional Chinese Medicine and
Pharmacy
汪海珍1，杨志波1
（通讯作者），罗美俊子2
（1.湖南中医药大学第二附属医院，湖南长沙410005；
2.湖南中医药大学2011级硕士研究生，
周宝宽湖南长沙410208）[摘要]
目的：探讨湿疹纳米乳膏联合四物消风饮慢性局限性湿疹的临床疗效。方法：将55例患者随机分为两组，治始祖鸟化石
疗组28例给予湿疹纳米乳膏联合四物消风饮，对照组27例予尤卓尔软膏，观察比较两组第1、2、3周后的疗效。结果：两组在第1、2周后疗效比较，差异无统计学意义（P ＞0.05）；第3周后组总有效率为89.3％，对照组有效率为66.7％，差异有统计学意义（P ＜0.05）
。结论：湿疹纳米乳膏联合四物消风饮慢性局限性湿疹疗效确切。[关键词]湿疹纳米乳膏；四物消风饮；慢性局限性湿疹
[中图分类号]R275.9[文献标识码]A [文章编号]1672-951X （2013）01-0034-02
Effect of Combination of Eczema Nano Cream and Siwu Xiaofeng Powder on Chronic
Localized Eczema:A Clinical Research of 55Cases大鼠灌胃
PINGCOWANG Hai-zhen 1,YANG Zhi-bo 1(Corresponding Author),LUO Mei-jun-zi 2
(1.The Second Affiliated Hospital of Hunan University of Chinese Medicine,Changsha 410005,China;2.Master Degree Candidate in Grade 2011,Hunan University of Chinese Medicine,Changsha 410208,China)[Abstact]
Objective:To observe effect of combination of eczema nano cream and Siwu Xiaofeng powder on chronic
localized eczema.Methods:55patients were randomly divided into two groups,the 28cases in the treatment group were treated with combination of eczema nano cream and Siwu Xiaofeng powder;the 27cases in control group were given Youzhuoer ointment treatment;the comparsion of effect were carried out at the first,second and third weeks.Results:In the comparsion of effect bwtween the two groups at the first and second weeks,there was no significant difference(P >0.05);the effective rate was 89.3%in treatment group,66.7%in control group,at the third week,and the difference was statistically significant(P <0.05).Conclusion:The conbination of eczema nano cream and Siwu Xiaofeng powder can provide good therapeutic effect on chronic localized eczema.
[Key word]
Eczema Nano Cream;Siwu Xiaofeng powder;Chronic localized eczema
慢性局限性湿疹以多形性皮肤损害为主要表现，患者多自觉瘙痒，可发生于身体任何部位，但以手足、小腿等处常见[1]。本病发病原因不明确，易反复发作，经久不愈。2010年6月到2012年7月我科在该病的上采取院内自制湿疹纳米乳膏外用联合四物消风饮内服，取得了较满意的疗效，具体报告如下。1
资料与方法
1.1纳入标准皮损面积小于10%，
皮损表现为浸润肥厚、
脱屑、素沉着、苔藓样变；年龄在18-65岁之间，性别不限；自愿参加本临床观察。
半角字符1.2排除标准存在心脑血管、
肝、肾和造血系统等严重原发疾病；2周内使用与本病有关的中西
药物或外法；免疫功能低下者；孕妇。1.3一般资料患者来自于湖南中医药大学第二附属医院皮肤科，将符合慢性局限性湿疹纳入标准的共55例随机分为组和对照组。组将28例，男17例，女11例；平均年龄（42.6±6.6）岁。对照组27例，男15例，女12例；平均年龄（43.6±6.6）岁。
*基金项目：
刘韧磊“十一五”国家科技支撑计划（2008BAI53B042
）
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