专利名称：NUCLEIC ACID SEQUENCES THAT CAN BE USED AS PRIMERS AND PROBES IN THE AMPLIFICATION AND DETECTION OF ALL
流鬼国SUBTYPES OF HIV-1
发明人：GOUDSMIT, Jaap,OUDSHOORN,
Pieter,JURRIAANS, Suzanne,LUKASHOV,
Vladimir Vladimirovich
申请号：EP1998004945
申请日：19980805
公开号：WO99/007898P1
南澳1号公开日：
ODF19990218
摘要：The present invention is related to nucleic acid sequences that can be used in the field of virus diagnostics, more specifically the diagnosis of infections with the AIDS causing Human Immuno-deficiency Virus (HIV). With the present invention nucleotide sequences are provided that can be used as primers and probes in the amplification and detection of HIV-1 nucleic acid. The oligonucleotide sequences provided with the present invention are located in the LTR part of the HIV viral genome. It has been found that, by using the sequences of the present invention in methods for the amplification and detection of nucleic acid a sensitive and specific detection of HIV-1 can be obta
ined. The benefit of the sequences of the present invention primarily resides in the fact that, with the aid of primers and probes comprising the sequences according to the invention the nucleic acid of all presently known subtypes of HIV-1 can be detected with high accuracy and sensitivity. So far no primer pairs or hybridization probes have been developed that
tftlcd接口
would allow the detection of such a broad range of HIV-1 variants. The oligonucleotide sequences according to the present invention are especially useful in methods for the amplification of nucleic acid.
申请人：GOUDSMIT, Jaap,OUDSHOORN, Pieter,JURRIAANS, Suzanne,LUKASHOV, Vladimir Vladimirovich减肥行为疗法
地址：NL,NL,NL,NL,NL
国籍：NL,NL,NL,NL,NL
代理机构：VAN GENT, M.
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