毕业设计
题 目 年产一亿颗盐酸多奈哌齐胶囊的车间设计
学院名称 化学化工学院
指导教师 胸针设计
职 称 教 授
班 级 制药工程11级2班
学 号
学生姓名 光缆接线盒
烘干窑
2015年05月31 日
压电陶瓷驱动器年产一亿颗盐酸多奈哌齐胶囊的生产车间设计
摘要：盐酸多奈哌齐是属于第二代乙酰胆碱酯酶抑制剂，它能可逆性地抑制乙酰胆碱酯酶所引起的乙酰胆碱水解，从而增加受体部位的乙酰胆碱酯含量，进而增强乙酰胆碱的生理作用。临床上作为阿尔兹海默症的首选药物。本设计从可行性出发，设计了年产一亿颗盐酸多奈哌齐胶囊剂的工艺流程、物料衡算、设备选型、平面布置等。本着符合GMP要求、可操作性的角度出发，设计有一般中小型制药厂所需具备的简单、经济、合理、安全等优良性质。通过此次毕业设计，使所学理论知识运用到实际设计中来，大大锻炼了学生能力。
关键词： 盐酸多奈哌齐；工艺流程； 物料衡算； 生产设备； 车间布置
窗体顶端威尔逊氏病
Abstract: donepezil hydrochloride belongs to the second generation acetylcholinesterase inhibitor that reversibly inhibit the hydrolysis of acetylcholine caused by acetylcholinesterase, thereby increasing acetylcholine receptor sites ester content, thus enhancing the physiological role of acetylcholine. As the drug of choice for the treatment of Alzheimer's disease clinically. This design starting from feasibility, design process one hundred million annual donepezil hydrochloride capsules, material balance, equipment selection, layout and so on. In the GMP requirements, operational point of view, the design of most small and medium pharmaceutical required of simple good nature of economic, reasonable, and security. With this graduation project, so that the theory of knowledge into actual design to greatly exercise the students' ability.窗体底端
iphd
窗体顶端
Abstract: donepezil hydrochloride belongs to the second generation acetylcholinesterase inhibitor that reversibly inhibit the hydrolysis of acetylcholine caused by acetylcholinesterase, thereby increasing acetylcholine receptor sites ester content, thus enhancing the physiological role of acetylcholine. As the drug of choice for the treatment of Alzheimer's disease clinically. This design starting from feasibility, design process one hundred million annual donepezil hydrochloride capsules, material balance, equipment selection, layout and so on. In the GMP requirements, operational point of view, the design of most small and medium pharmaceutical required of simple good nature of economic, reasonable, and security. With this graduation project, so that the theory of knowledge into actual design to greatly exercise the students' ability.窗体顶端
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