上海市松江区结直肠癌发病危险因素研究

www.chinagp  E-mail:zgqkyx@chinagp
·3709·
石墨烯设备·论著·上海市松江区直肠癌发病危险因素研究
郁雨婷1,赵根明1,郁建国2,陶沙1*
【摘要】 背景 上海市结直肠癌发病率和在恶性肿瘤中的死亡顺位从20世纪70年代起逐步上升,严重危害了
上海市居民的身体健康,成为重大的公共卫生问题。目的 探究上海市松江区结直肠癌的发病危险因素,为开展针对
性的干预措施提供科学依据。方法 选取2015年上海市松江区50~74岁的常住人口。病例组为社区结直肠癌筛查发
现的结直肠癌及癌前患者330例,对照组为参加结直肠癌筛查且初筛阴性的社区居民1016例。根据上海市大肠癌筛
查项目工作规范,经社区居民知情同意采取问卷调查结合胶体金免疫便隐血试验的方案进行初筛。问卷调查部分采用
局域表面等离子体共振
上海市统一的《上海市社区居民结直肠癌筛查危险度评估问卷》,由松江区疾病预防控制人员和中山社区医务人员对
调查对象进行面对面问卷调查,内容包括个人基本信息(年龄、婚姻、文化程度)、BMI(BMI<18.5 kg/m2为低体质量,18.5~23.9 kg/m2为正常体质量,24.0~27.9 kg/m2为超重,≥28.0 kg/m2为肥胖)、既往疾病史、生活习惯(吸烟、生活
/工作中二手烟、饮酒情况)、工作情况。探讨上海市松江区结直肠癌发病的危险因素。结果 单因素分析显示,肥胖、
慢性腹泻、黏液/血便、慢性阑尾炎/切除、结核病史、高血压、肠息肉史、生活/工作中二手烟为结直肠癌的影响因
素(P<0.05);多因素Logistic回归分析结果显示,对于全人而言,年龄、慢性腹泻、结核病史、肠息肉史、吸烟
潜流带
为结直肠癌的危险因素(P<0.05);对于不吸烟的人而言,年龄、慢性腹泻、肠息肉史和生活/工作
中二手烟为结
直肠癌的危险因素(P<0.05)。结论 年龄、慢性腹泻、结核病史、肠息肉史和吸烟为上海市松江区居民结直肠癌发
病的危险因素,应加强对上述相关人的早期干预。
【关键词】 结直肠肿瘤;危险因素;上海
【中图分类号】 R 735.34 【文献标识码】 A DOI:10.12114/j.issn.1007-9572.2018.00.234
动物胶配方整个过程
郁雨婷,赵根明,郁建国,等.上海市松江区结直肠癌发病危险因素研究[J].中国全科医学,2018,21(30):3709-3713.[www.chinagp]
YU Y T,ZHAO G M,YU J G,et al.Risk factors of colorectal cancer in Songjiang District,Shanghai[J].Chinese General Practice,2018,21(30):3709-3713.
柔性触觉传感器Risk Factors of Colorectal Cancer in Songjiang District,Shanghai YU Yuting1,ZHAO Genming1,YU Jianguo2,TAO
Sha1*
1.School of Public Health,Fudan University,Shanghai 200032,China
2.Songjiang District Zhongshan Community Health Center,Shanghai 201613,China
*Corresponding author:TAO Sha,Associate research fellow;E-mail:taosha@fudan.edu
【Abstract】 Background The morbidity and mortality of colorectal cancer in Shanghai have risen gradually since
the 1970s,which seriously harm the health of the residents in Shanghai and become a serious public health problem.Objective
封条锁
 To explore the risk factors of colorectal cancer in Songjiang District of Shanghai,providing scientific evidence for the delivery of targeted preventive interventions.Methods We conducted this study among the permanent residents aged 50-74
from Shanghai's Songjiang District after obtaining their informed consent in accordance with the regulations for implementing
a colorectal cancer screening in Shanghai 2015.All of them underwent fecal occult blood test by colloidal gold agglutination.
From them,we enrolled 330 cases who were found with colorectal cancer or precancerous colorectal lesions(case group),
and compared them with randomly selected sex-matched 1016 controls with normal test results(control group).Then,both
groups participated in a face-to-face survey with a questionnaire named Screening for the Risk Factors of Colorectal Cancer in Shanghai's Residents conducted by the workers from Songjiang Center for disease control and prevention and medical professionals
from Songjiang District Zhongshan Community Health Center.The questionnaire consists of demographic data such as age,
marital status,educational level,BMI(underweight:<18.5 kg/m2,normal weight:18.5-23.9 kg/m2,overweight:24.0-27.9 kg/m2,obese:≥28.0 kg/m2),past medical history,life habits(active smoking and passive smoking in everyday life
or at work,alcohol consumption) and employment status.And the risk factors of colorectal cancer were investigated.Results 
1.200032上海市,复旦大学公共卫生学院
2.201613上海市松江区中山社区卫生服务中心
*通信作者:陶沙,副研究员;E-mail:taosha@fudan.edu

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