小剂量用于瑞麻醉后痛觉过敏的临床研究作者：汪忠玉 魏 薇 郑利民来源：《中国实用医药》2009年第04仓库管理流程期 【摘要】 水质快速检测
目的 观察小剂量是否能抑制瑞复合吸入麻醉所致的痛觉过敏。方法 腹腔镜下胆囊切除术患者60例，20～60岁，ASA分级Ilc-a～电磁感应锅炉II级，随机分为3组：对照组(C组)术中仅用吸入麻醉；瑞组(R组)术中持续靶控输注靶浓度4 μg/L的瑞；组柴油机起动器(K组)术中持续靶控输注靶浓度4 μg/L的瑞，缝皮时给予0.5 mg/kg。记录3组患者拔管时间、拔除气管导管后的口述疼痛评分，拔管后2、4、12、24 h的视觉疼痛模拟评分(VAS)，4 h内再次要求镇痛的人数和拔管后24 h内的不良反应。结果 R组和K组患者苏醒和拔管时间显著短于C组(P 【关键词】瑞；； 痛觉过敏
Effects of ketamine on the patients with postoperative hyperalgesia after remifentanil-based anaesthesia
WANG Zhong-yu，WEI Wei，ZHENG Li-min.Department of Anesthesiology, Beijing University Shenzhen Hospital, Shenzhen 518036, China
除铁 【Abstract】 Objective To evaluate the preventive effects of ketamine on the patients with postoperative hyperalgesia after large-dose remifentanil-based anesthesia．Methods 60 patients undergoing laparoscopic cholecystectomy were randomly assigned to 3 groups (n=20)，group R received intraoperative remifentanil by TCI at 4μg/L, group K received intraoperative remifentanil by TCI at 4 μg/L and ketamine 0.5 mg/kg at skin closure, group C received no drug infusion. Anesthesia was maintained with sevoflurane. The four-level verbal rating scale after trachea extubation，VAS score at 2，4，12，24 hours after extubation were recorded. Results The emergence times were significantly shorter in the Group R and Group K than those in Group C(P
豫公网安备41160202000603
站长QQ:729038198
关于我们
投诉建议