2013-2017专利到期药品

Active IngredientsLocal Brand NameLocal MarketersMerck TCgefitinib吉非替尼IRESSAASTRAZENECAAntineoplasticpaliperidone palmitate棕榈酸帕潘立酮INVEGA SUSTENNAJANSSEN PHARMdesvenlafaxine succinatemonohydrate琥珀酸去甲文拉法辛PRISTIQPFIZERzoledronic acid唑来膦酸ZOMETAAntipsychoticAntidepressantAntiosteoporotic; Antipagetic;Bone Resorptionprednisolone acetate醋酸泼尼松ibuprofen lysine布洛芬赖氨酸盐ECONOPREDNEOPROFENdecitabine地西他滨DACOGENinsulin lispro recombinant赖脯胰岛素HUMALOGrabeprazole sodium雷贝拉唑钠zolmitriptan佐米曲普坦efavirenz依非韦伦ACIPHEXZOMIGSUSTIVAduloxetine hydrochloride度洛西汀CYMBALTAtigecycline替加环素TYGACILdexmedetomidine hydrochloride右美托咪定PRECEDEXertapenem sodium厄他培南钠INVANZsevelamer carbonate碳酸司维拉姆imiglucerase伊米苷酶RENVELACEREDASENOVARTIS RXA-ASPECTRUM;WATSONLABS;TEVAPHARMACEUTICA;TARO PHARM;STERISGlucocorticoidAnti-InflammatoryLUNDBECK PHARM(Nonsteroidal);Antineoplastic;EISAI INCAntiviralLILLYAntidiabeticAntiulcerative;Gastric ProtonEISAI INCPump InhibitorAntimigraine;SerotoninASTRAZENECAReceptor AgonistAntiviral;ReverseDUPONT PHARMTranscriptaseAntidepressant;SerotoninLILLYNoradrenalineAntibacterialPFIZER(Antibiotic)Sedative/Hypnotic; AdrenergicHOSPIRAAgonist (Alpha-AntibacterialMERCK & COMPANY(Antibiotic)AntihyperphosphaGENZYME CORPtemicGENZYME CORP

mycophenolate mofetilhydrochloride麦考酚酸酯capecitabine卡培他滨telmisartan替米沙坦ritonavir.利托那韦CELLCEPTXELODAMICARDISNORVIRENDO GENERICPROD;ROCHEROCHEImmunosuppressant; Anti-InflammatoryAntineoplasticAntihypertensive; Angiotensin IIBOEHRINGER INGELReceptorAntiviral; HIVABBOTT PHARMProteinasePRODSInhibitor;NOVO NORDISKAntidiabeticALCONOPHTHALMICS;SCHERINGAntibacterialAntigout;Xanthine OxidaseTAKEDA PHARM USAInhibitorImmunosuppressanNOVARTIS RXtAXCANDiagnostic AidSCANDIPHARM;X-(RadiopaqueGEN PHARMMedium); EnzymeTEVAImmunomodulator;NEUROSCIENCENeuroprotectiveAnti-InflammatoryPFIZER(Nonsteroidal);PFIZERABBOTT PHARMPRODSGSK PHARMSANOFI AVENTISPHRAntineoplasticAntiosteoporotic;AntihyperparathyAntithrombotic;Anticoagulantinsulin detemir地特胰岛素LEVEMIRmoxifloxacin hydrochloride莫西沙星AVELOXfebuxostat非布索坦everolimus依维莫司pancrelipase胰脂肪酶glatiramer acetate格拉替雷ULORICAFINITORCOTAZYMCOPAXONEcelecoxib塞利昔布temsirolimus西罗莫司脂化物paricalcitol帕立骨化醇argatroban阿加曲班CELEBREXTORISELZEMPLARLaunched withgeneric namedronedarone hydrochloride决奈达隆MULTAQAntiarrhythmicprasugrel hydrochloride普拉格雷lubiprostone鲁比前列酮lacosamide拉科酰胺bimatoprost比马前列素EFFIENTAMITIZAVIMPATLUMIGANLILLYLaxative/CathartTAKEDA PHARM USAicAnticonvulsant;SCHWARZ PHARMAAnalgesicAntiglaucoma;Prostaglandin/PrALLERGANostaglandinAntifungal(Synthetic)Antineoplastic(Hormonal);Somatostatinposaconazole泊沙康唑lanreotide acetate兰瑞肽NOXAFILSCHERINGSOMATULINE DEPOTTERCICA, INC

adefovir dipivoxil阿德福韦酯sevelamer hydrochloride司维拉姆bortezomib硼替佐米HEPSERARENAGELVELCADEGILEAD SCIENCESAntiviralAntihyperphosphaGENZYME CORPtemicMILLENNIUM PHARMAntineoplasticDAIICHI SANKYOAntilipemic;INCCardiotonicAntithrombotic;SCHERINGAntianginalALCONOPHTHALMICSAntiglaucomaNOVO NORDISKSANOFI AVENTISPHRBRISTOL-M SQ USPHAntidiabeticAntidiabeticcolesevelam hydrochloride考来维仑WELCHOLeptifibatide依非巴特INTEGRILINtravoprost曲伏前列腺素insulin aspart门冬胰岛素insulin glargine甘精胰岛素TRAVATANNOVOLOGLANTUSentecavir恩替卡韦BARACLUDElevoleucovorin calcium左旋亚叶酸钙FUSILEVdarifenacin hydrobromide达非那新ENABLEXbendamustine hydrochloride苯达莫司汀TREANDApalonosetron hydrochloride帕洛诺司琼ALOXIaripiprazole阿立哌唑linezolid利奈唑胺doripenem多尼培南follitropin alfa促卵泡素follitropin betaimatinib mesylate伊马替尼ABILIFYZYVOXDORIBAXGONAL-FFOLLISTIMGLEEVECAntiviralAntiemetic;AntineoplasticSPECTRUM PHARMAdjunctAntispasmodic;Uricosuric;WARNER-CHILCOTTAntimuscarinicCEPHALON INCOTSUKA AMERICAPHPFIZERORTHO PHARMEMD SERONOORGANONNOVARTIS RXROCHEROCHEAMGEN INCORTHO PHARMAntineoplasticAntiemetic;SerotoninReceptorAntipsychotic;Dopamine-Serotonin SystemAntibacterial(Synthetic)AntibacterialGonad-StimulatingPrincipleGonad-StimulatingPrincipleAntineoplasticAntiviral;NeuraminidaseInhibitorAntiviralAntihyperparathyroidAntimigraine;SerotoninReceptor Agonistoseltamivir phosphate磷酸奥司他韦TAMIFLUvalganciclovir hydrochloride缬更昔洛韦VALCYTEcinacalcet hydrochloride西那卡塞SENSIPARalmotriptan malate依来曲普坦AXERT

frovatriptan succinate琥珀酸福伐曲坦FROVAbosentan波生坦dutasteride度他雄胺thyrotropin alfa促甲状腺激素estradiol acetate雌二醇pitavastatin calcium匹伐他汀钙cabazitaxel卡巴他赛emtricitabine恩曲他滨gatifloxacin加替沙星rosuvastatin calcium瑞舒伐他汀lenalidomide来那度胺TRACLEERAVODARTTHYROGENFEMRINGLIVALOJEVTANA KITEMTRIVAZYMARCRESTORREVLIMIDENDO LABSACTELION PHARMGSK PHARMGENZYME CORPAntimigraine;SerotoninReceptor AgonistCardiotonic;Antihypertensive; EndothelinAntiprostaticHypertrophy;5Alpha-ReductaseThyroid HormoneWARNER-CHILCOTTEstrogenAntilipemic; HMGCoA ReductaseLILLYInhibitorSANOFI AVENTISPHRGILEAD SCIENCESALLERGAN;BRISTOL-M SQ US PHASTRAZENECACELGENEA-SMEDICATION;XANODYNE PHARMA;WESTFSC LABORATORIESIARISTOSPHARM;CORNERSTONE THERAPDAIICHI SANKYOINCSUNOVIONAMYLIN PHARMNOVARTIS RXPFIZERLILLYTEVANEUROSCIENCENOVARTIS RXAntiviralAntibacterial(Synthetic)Antilipemic; HMGCoA ReductaseInhibitorImmunomodulatorAntigout;AnalgesicAntibacterial(Synthetic)Antibacterial(Antibiotic)Antihypertensive; Angiotensin IIReceptorBronchodilator;AntiasthmaticAntidiabeticAntibacterial(Antibiotic);ImmunosuppressanAntimigraine;SerotoninReceptor AgonistAntineoplasticAntiparkinsonianAntineoplastic;Immunosuppressant; IMPDHcolchicine秋水仙碱COLCRYStrimethoprim hydrochloride甲氧苄氨嘧啶PRIMSOLcefditoren pivoxil头孢妥仑匹酯SPECTRACEFolmesartan medoxomil奥美沙坦酯BENICARarformoterol tartrate酒石酸阿福特罗BROVANAexenatide艾塞那肽pimecrolimus吡美莫司BYETTAELIDELeletriptan hydrobromide依来曲普坦RELPAXpemetrexed disodium培美曲塞ALIMTArasagiline mesylate甲磺酸雷沙吉兰AZILECTmycophenolic acid麦考酚酸MYFORTIC

sinecatechins赛儿茶素ezetimibe依泽替麦VEREGENZETIAnaltrexone纳曲酮VIVITROLparoxetine mesylate甲磺酸帕罗西汀PEXEVAatazanavir sulfate阿扎那韦REYATAZtenofovir disoproxil fumarate富马酸泰诺福韦酯VIREADliraglutide利拉鲁肽RIES;TEVAPHARMACEUTICA;PRIVATEAntiviralMERCK/SCHERING-PLGAntilipemicAlcoholDependenceALKERMES INCTreatment;Antidepressant;Serotonin UptakeNOVEN PHARMInhibitor;Antiviral; HIVProteinaseBRISTOL-M SQ HIVInhibitorReverseTranscriptaseGILEAD SCIENCESInhibitorNOVO NORDISKAntidiabeticciclesonide环索奈德tadalafil他达拉非OMNARISCIALISfosamprenavir calcium福沙那伟钙LEXIVAbepotastine benzenesulfonate salt贝托司汀BEPREVEGlucocorticoid;SUNOVIONAntiasthmaticPhosphodiesterase Inhibitor;LILLYImpotenceAntiviral; HIVProteinaseVIIV HEALTHCAREInhibitorISTA PHARMAntihistaminic

Thomson Reuters Newport PremiumSearch ResultsEphMRA TCRoute ofAdministrationDose FormFirstNewportConstraint DateSPCExpir19-Jan-13AntineoplasticsOralTabletPsycholepticsPsychoanalepticsExcluding Anti-ObesityOther Drugs ForDisorders Of TheMusculo-SkeletalAll OtherTherapeuticProducts;TopicalCorticosteroids;Analgesics;Topical Anti-Rheumatics;Antineoplastics;Antivirals ForSystemic UseDrugs Used InDiabetesAntacids,Antiflatulentsand Anti-AnalgesicsAnti-Inflammatory AndAnti-RheumaticOther CNS Drugs;Urologicals;PsychoanalepticsSystemicAntibacterialsAnaesthetics;PsycholepticsOther Anti-Infectives;SystemicAll OtherTherapeuticProductsAll OtherTherapeuticProductsParenteralOralParenteralInjectableTablet, Delayed31-Jan-13Release;Tablet,Extended Release1-Mar-13Injectable2-Mar-13Injectable;Tablet;Suspension;PowOphthalmic;Parender;Liquid/Dropsteral;Other;Oral;Liquid11-Mar-13ParenteralParenteralParenteralOralNasal;OralOralOralParenteralParenteralParenteralOralParenteralInjectableInjectable13-Apr-132-May-13Injectable7-May-13Tablet, DelayedRelease8-May-13Spray;Tablet,OrallyDisintegrating;T14-May-13Capsule;Tablet21-May-13Capsule, DelayedRelease11-Jun-13InjectableInjectableInjectablePowder;TabletInjectable25-Jun-1315-Jul-132-Aug-1311-Aug-1327-Aug-13

Anti-Asthma andCOPD Products;Capsule;InjectabUrologicals;Oral;Parenteralle15-Sep-13AntineoplasticsAgents Acting OnThe Renin-AngiotensinAntivirals ForSystemic Use;BloodDrugs Used InDiabetesOphthalmologicals; SystemicAntibacterialsAnti-GoutPreparationsAntineoplastics;ImmunosuppressantsAll OtherTherapeuticProducts;Immunostimulating Agents; OtherCNS DrugsAnalgesics;Antineoplastics;Anti-AntineoplasticAndImmunomodulatingOther Drugs ForDisorders Of TheMusculo-SkeletalAntithromboticAgents; CardiacTherapyOralOralOralTablet14-Dec-13Tablet7-Jan-14Capsule;Tablet;Liquid30-Jan-14ParenteralInjectable2-Feb-14Ophthalmic;ParenInjectable;Tableteral;Oralt;Liquid/Drops4-Mar-14OralOralOralParenteralTablet25-Mar-14TabletCapsule;Tablet,30-Mar-14ExtendedRelease;Tablet;C30-Apr-14Injectable24-May-14OralParenteralCapsule30-May-14Injectable30-May-14Capsule;InjectabOral;Parenteralle24-Jun-14ParenteralInjectable30-Jun-14Cardiac TherapyOralAntithromboticAgentsTablet1-Jul-14OralTablet10-Jul-14LaxativesOralAnalgesics;Anti-EpilepticsOral;ParenteralOphthalmologicalsAntiprotozoalsOphthalmicandAnthelmintics;Systemic AgentsCardiac Therapy;OralPituitary AndHypothalamicParenteralCapsule14-Jul-14Injectable;Tablet;Liquid5-Aug-14Liquid/Drops20-Aug-14SuspensionInjectable26-Aug-1430-Aug-14

Antivirals ForSystemic Use;SystemicAll OtherTherapeuticProductsAntineoplasticAndImmunomodulatingLipid-Regulating/Anti-AtheromaAntithromboticAgents; CardiacTherapyOphthalmologicalsDrugs Used InDiabetesDrugs Used InDiabetesAntivirals ForSystemic UseAll OtherTherapeuticProducts;Antidiarrhoeals,Oral ElectrolyteReplacers andAnalgesics;AntineoplasticsOralOralParenteralOralParenteralOphthalmicParenteralParenteralOralParenteralOralParenteralParenteralTabletCapsule;TabletInjectableGranule;TabletInjectableLiquid/DropsInjectableInjectableLiquid;Tablet2-Sep-1416-Sep-1428-Oct-1429-Oct-1411-Nov-142-Dec-147-Dec-1412-Feb-1521-Feb-15Injectable7-Mar-15Tablet, ExtendedRelease13-Mar-15Injectable20-Mar-15PsycholepticsAnalgesics;SystemicAntibacterialsSystemicAntibacterialsSex Hormones AndProducts WithSimilar DesiredSex Hormones AndProducts WithSimilar DesiredAntineoplastics;PsycholepticsAntivirals ForSystemic Use;Cough And ColdAntivirals ForSystemic UseThyroid Therapy;VitaminsAnalgesicsInjectableInjectable;Table13-Apr-15t, OrallyOral;ParenteralDisintegrating;T20-Apr-15Injectable;TableOral;Parenteralt;Suspension18-May-15ParenteralParenteralParenteralOralOralOralOralOralInjectableInjectableInjectable5-Jun-1516-Jun-1516-Jun-15Capsule;Tablet4-Jul-15Capsule;Suspension27-Aug-15Suspension;Tablet29-Sep-15TabletTablet23-Oct-157-Nov-15

AnalgesicsAntihypertensiveOrals; OtherCardiovascularOralUrologicalsDiagnosticImaging; ThyroidTherapy;Sex Hormones AndProducts WithSimilar DesiredLipid-Regulating/Anti-AtheromaAntineoplasticsAntivirals ForSystemic UseOphthalmological/OtologicalCombinations;Lipid-Regulating/Anti-AtheromaAntineoplasticAndImmunomodulatingAll OtherTherapeuticProducts;SystemicAntibacterialsSystemicAntibacterialsAgents Acting OnThe Renin-AngiotensinAnti-Asthma andCOPD ProductsDrugs Used InDiabetesNonsteroidalProducts forInflammatoryAnalgesicsAntineoplasticAndImmunomodulatingAnti-ParkinsonDrugsAntineoplasticAndImmunomodulatingOralParenteralOral;OtherOralParenteralTabletTabletCapsuleInjectableOther SpecialForms;TabletTabletInjectable7-Nov-1520-Nov-1520-Nov-1524-Nov-1519-Dec-1529-Dec-1526-Mar-16OralCapsule;Liquid29-Mar-16Ophthalmic;ParenInjectable;Tableteral;Oralt;Liquid/Drops5-Jun-16OralTablet8-Jul-16OralCapsule24-Jul-16Oral;Parenteral;Injectable;TableOthert;Powder29-Jul-16OralOralOralInhaleParenteralTopicalOralParenteralOralOralLiquidTabletTabletAerosolInjectableCreamTabletInjectable7-Aug-1614-Oct-1625-Oct-1612-Nov-161-Dec-1615-Dec-1626-Dec-1624-Jan-17Tablet7-Feb-17Tablet;Tablet,Delayed Release10-Apr-17

All OtherTherapeuticProducts;Vitamins;Lipid-Regulating/Anti-AtheromaAll OtherTherapeuticProducts; OtherPsychoanalepticsExcluding Anti-ObesityAntivirals ForSystemic Use;BloodAntivirals ForSystemic UseDrugs Used InDiabetesAnti-Asthma andCOPD Products;SystemicCorticosteroids;OtherCardiovascularProducts;Antivirals ForSystemic Use;BloodAnti-Asthma andCOPD Products;SystemicOralOralParenteralOralOralOralParenteralCapsule;Tablet;Gum,Chewing;Granule10-Apr-17TabletInjectableTabletCapsuleTabletInjectableAerosol,Metered;Spray25-Apr-172-May-1710-Jun-1720-Jun-1725-Jul-1722-Aug-17Inhale;NasalOralOralOphthalmic24-Oct-17Tablet21-Nov-17Suspension;Tablet24-Dec-17Liquid/Drops25-Dec-17© THOMSON REUTERS 2011

First PriorityDate20-Jan-92First ProductTechnologyCAS NumberPatent EstimatedTherapeutic UsesNon-small cellInfusion; TabletExpirylung cancer,formulation;ContinuedSmall molecule19-Jan-13monotherapy intherapeutic;184475-35-27-Nov-888-Jan-071-Aug-8619-Oct-10Bone metastasisEnteric coated- Solid tumorformulation;configurationTablet199739-10-1386750-22-7165800-06-624-Jul-074-Aug-0552-21-157469-77-92353-33-5133107-64-9117976-90-6139264-17-8154598-52-4136434-34-9220620-09-7145108-58-3153832-38-3845273-93-0154248-97-224-Jul-989-Feb-8913-Nov-867-Jun-907-Aug-9222-Dec-864-Oct-917-Aug-794-Feb-9211-Aug-9323-Dec-887-May-1310-Nov-0721-Mar-127-Aug-1211-Sep-0727-Feb-1315-Jul-132-Feb-1311-Aug-1317-Aug-10Myelodysplasticsyndrome (A)Diabetesmellitus type 1(A, P); DiabetesDuodenal ulcerdisease (A);GastroesophagealMigraine (A)HIV infection(A, P)Diabeticperipheralneuropathy -Communityacquiredpneumonia (A);Sedation,Intubated/mechanicallyCommunityacquiredpneumonia (A,Non-neuropathicGaucher'sdisease,Infusion; Smallmoleculetherapeutic;Biologicaltherapeutic;SubcutaneousCapsuleformulation;TabletNasal systemicformulation;TransdermalCapsuleformulation;TabletCapsuleformulation;Small moleculeAntibiotic;Small moleculetherapeutic;Buccalformulation,local;Antibiotic;Small moleculetherapeutic;Oralformulation;TabletBiologicaltherapeutic;Small molecule

30-Jan-8717-Nov-876-Feb-9123-May-8917-Sep-9315-Jul-8830-Nov-906-Jun-8928-Jul-0821-Apr-7130-Jan-0713-Jan-117-Jan-1423-May-092-Feb-1430-Jun-0925-Mar-1424-Sep-1324-May-1422-Sep-9218-Apr-949-Mar-8914-Oct-7530-Nov-1318-Apr-149-Mar-0919-Apr-946-Aug-9026-Jul-11Cardiactransplantrejection;Colon cancer,Adjuvanttherapy, Duke'sCardiovascularevent risk,Reduction (A);HIV infection(A, P)Diabetesmellitus type 1(A, P); DiabetesAcute infectiveexacerbation ofchronicGout -Hyperuricemia(A)Renal cellcarcinoma,Advanced diseasePancreaticinsufficiency(A, P)RelapsingremittingmultipleAnkylosingspondylitis (A);RheumatoidRenal cellcarcinoma,Advanced (A)Renalimpairment,chronic -Coronary arterythrombosis, Inpatients with orAtrialfibrillation,Paroxysmal orPersistent (A);Oralformulation;Small moleculeOralformulation;TabletNanoparticleformulation,oral; TabletCapsuleformulation;TabletBiologicaltherapeutic;SubcutaneousAntibiotic;Tabletformulation;Oralformulation;Small moleculeOralformulation;TabletBiologicaltherapeutic;OralBiologicaltherapeutic;SubcutaneousCapsuleformulation;SustainedIntravenousformulation;Small moleculeCapsuleformulation;Small moleculeInjectableformulation;Small moleculeFilm coating;Tabletformulation;Small molecule116680-01-4154361-50-9144701-48-4155213-67-5169148-63-4186826-86-8144060-53-7159351-69-653608-75-6147245-92-9169590-42-5162635-04-3131918-61-1141396-28-3141625-93-628-Jan-8715-Feb-8521-Sep-9228-Jan-083-Jan-1221-Sep-12Constipation -Irritable bowelsyndrome (A);Partial seizure;Adjunct (A)Hypotrichosis,Of the eyelashes(A); Open-angleAspergillosis,Invasive, inhigh-riskpatients;Acromegaly (A)Capsuleformulation;Small moleculeInfusion; Tabletformulation;Solution; SmallOphthalmicformulation;Small moleculeIntravenousformulation;Small moleculetherapeutic;Biologicaltherapeutic;Sustained389574-19-0136790-76-6175481-36-4155206-00-121-Dec-9312-Sep-852-Dec-14171228-49-2127984-74-1

25-Apr-8525-Apr-0628-Oct-942-Jun-9316-Jun-893-Aug-9325-Feb-8112-Mar-8518-Oct-903-Sep-8617-Mar-899-Aug-0028-Nov-8930-Mar-789-Sep-9320-Aug-912-Nov-832-Nov-833-Apr-9227-Feb-9519-Dec-8823-Aug-9128-Jul-9228-Oct-142-Jun-137-Jun-113-Aug-137-Dec-146-May-1023-Aug-11Type B viralhepatitis,chronic (A, P)End stage renaldisease -Hemodialysis -Mantle celllymphoma, Inpatients whoDiabetesmellitus type 2;Adjunct (A);Acute coronarysyndrome (A);PercutaneousRaisedintraocularpressure, InDiabetesmellitus type 1(A, P); DiabetesDiabetesmellitus type 1(A, P); DiabetesAntimetaboliteoverdose, Folicacid antagonistBladder muscledysfunction -overactive (A)Chronic lymphoidleukemia (A);Non-Hodgkin'sChemotherapy-induced nauseaand vomiting,Autisticdisorder -PsychomotorCommunityacquiredpneumonia (A,Infectiousdisease ofabdomen,Femaleinfertility -ReproductiveAcute lymphoidleukemia,Relapsed/RefractInfluenza, Virustypes A and B(A, P);AIDS -Cytomegaloviralretinitis (A);Dialysisprocedure -RenalMigraine (A)Crystallineform; SystemicformulationOralformulation;TabletInfusion;Subcutaneousformulation;Oralformulation;TabletBiologicaltherapeutic;Peptide;Ophthalmicformulation;Small moleculeBiologicaltherapeutic;SubcutaneousBiologicaltherapeutic;SubcutaneousInjectableformulation;TabletOralformulation;TabletInfusion; Smallmoleculetherapeutic;Capsuleformulation;Small moleculeInjectableformulation;TabletAntibiotic;Tabletformulation;Antibiotic;Small moleculetherapeutic;Biologicaltherapeutic;SubcutaneousOralformulation;TabletCapsuleformulation;Small moleculeOralformulation;TabletOralformulation;TabletOralformulation;Small molecule142340-99-6182683-007179324-69-7182815-44-7148031-34-9157283-68-6116094-23-6160337-95-1209216-23-980433-71-2133099-07-73543-75-7135729-62-3129722-12-9165800-03-3148016-81-356832-30-5110909-60-9220127-57-11204255-11-8175865-59-5364782-34-3181183-52-813-Mar-1013-Apr-1529-Mar-059-Sep-1314-Aug-1220-Jun-0620-Jun-0615-Sep-1427-Feb-1518-Dec-0923-Feb-137-May-15

26-Jun-9113-Jun-9117-Sep-932-Nov-8316-Dec-1320-Nov-1517-Sep-1311-Dec-05Oralformulation;Migraine (A)TabletOralPulmonaryformulation;hypertension (A)Small moleculeCapsuleBenign prostaticformulation;hyperplasia (A)Small moleculeBiologicaltherapeutic;ProteinOralformulation;TabletInfusion; Smallmoleculetherapeutic;Capsuleformulation;Stereochemistry;Antibiotic;Solution; SmallmoleculeOralformulation;TabletCapsuleformulation;Small moleculeInfusion; Tabletformulation;Small moleculeOralformulation;Small moleculeAntibiotic;Small moleculetherapeutic;Ophthalmicformulation;TabletAerosolformulation,inhalant;Biologicaltherapeutic;TransdermalDermatologicalformulation;TabletOralformulation;Small moleculeInfusion; Smallmoleculetherapeutic;Oralformulation;TabletEnteric coatedformulation;Tablet158930-17-7157212-55-0164656-23-9194100-83-94245-41-420-Aug-871-Feb-931-Feb-9021-Jan-861-Jul-9124-Jul-967-May-978-Oct-9123-May-029-Oct-865-Apr-9124-May-939-Nov-8915-Oct-902-Jul-993-Jan-9030-Jan-8719-Aug-081-Feb-131-Feb-1027-Aug-0812-Jun-1224-Jul-16Hyperlipidemia(A)183133-96-2143491-57-0112811-59-3147098-20-2191732-72-664-86-88-Jul-1411-Nov-161-Dec-164-Oct-1113-Aug-13HIV infection(A, P)Bacterialconjunctivitis(A, P); UrinaryDisorder ofcardiovascularsystem, Primary;Multiplemyeloma, incombination withFamilialMediterraneanfever (A, P);Otitis media(P); Urinarytract infectiousBronchitis,chronic, AcutebacterialHypertension (A,P)ChronicobstructivepulmonaryDiabetesmellitus type 2,In patientsAtopicdermatitis,Second-lineMigraine (A)Malignantmesothelioma ofpleura, InParkinson'sdisease, Initialmonotherapy (A);117467-28-4144689-63-4200815-49-2141732-76-5137071-32-0177834-92-3150399-23-8161735-79-124280-93-121-Dec-10

9-Jul-939-Oct-8421-Mar-1414-May-16Familialhypercholesterolemia -Alcoholdependence (A);OpioidOralformulation;TabletIntramuscularformulation;Transdermal811420-59-4163222-33-116590-41-3217797-14-3229975-97-7202138-50-9204656-20-25-May-9225-Apr-855-May-869-Apr-1725-Apr-065-Feb-167-Sep-9021-Jan-949-Jan-1316-Jul-16CapsuleHIV infectionformulation;(A, P)Small moleculeHIV infectionDermatological(A, P); Type Bformulation;viral hepatitis,Vaginal gelBiologicaltherapeutic;Weekly dosing;AerosolAllergicformulation,rhinitis (A, P);dermatological;Asthma (A, P)TransdermalErectileOraldysfunction (A);formulation;PulmonaryTransmucosal126544-47-6171596-29-5226700-81-826-Dec-9625-Dec-17190786-44-8

Studied InBladdertumor;Uterinecervixtumor;StomachHotflashes;NeuropathicBonedisease;RheumatoidAllergy;Inflammatorydisease;Dermatologicaldisease;AsthmaAcutelymphoblasticleukemia;SolidDiabetesmellitusDyspepsia;Zollinger-Ellisonsyndrome;PepticClusterheadache;MigraineHIV infectionBackpain;Urinaryincontinence;PosBacterialinfection;Streptococcus pyogenesAnesthesia;PainHyperphosphatemia;Renal diseaseGaucherdisease;Gauchersdisease type

Autoimmunedisease;TransplantBreasttumor;Stomachtumor;SolidCerebrovascularischemia;Syndrome X;PolycysticHIV infectionDiabetesmellitusAbdominalabscess;Streptococcus pyogenesGoutAge relatedmaculardegeneration;UveExocrinepancreaticinsufficiency;PaCrohnsdisease;Opticneuritis;NeurodeAlzheimersdisease;UterinecervixBreasttumor;Solidtumor;Sarcoma;RhHyperparathyroidism;SecondaryhyperparathyroidAngina;Thrombosis;Thromboembolism;MyocardialConstipation;Irritable bowelsyndrome;IleusEpilepsy;Osteoarthritis;NeuropathicGlaucomaAspergillusinfection;Trypanosoma cruziinfection;ProphyAcromegaly;Restenosis;Renaltumor;Prostate

Cytomegalovirusinfection;PoxvirusHyperphosphatemia;Renal diseaseAcutemyelogenousleukemia;SquamouHypercholesterolemia;Non-insulindependentAngina;Thromboembolism;MyocardialGlaucoma;OcularhypertensionDiabetesmellitus;Non-insulinDiabetesmellitus;Non-insulinAnemia;Osteosarcoma;Colontumor;Cancer;BlaIrritable bowelsyndrome;Urinaryincontinence;OveChemotherapy-inducedemesis;Nausea;EmAttentiondeficithyperactivityBacterialinfection;Streptococcus pyogenesAcinetobacterinfection;StreptococcusFemaleinfertility;Maleinfertility;InfeFemaleinfertility;MaleinfertilityAcutelymphoblasticleukemia;ThyroidInfluenza virusinfectionCMVretinitis;UlcerativeHypercalcemia;SecondaryhyperparathyroidMigraine

MigraineCardiacfailure;Skinulcer;SclerodermAlopecia;Prostate tumor;ProstatehyperplasiaNodulargoiter;ThyroidtumorMenopauseBreasttumor;Stomachtumor;SolidHIVinfection;Hepatitis B virusBacterialinfection;StreptococcusAorticstenosis;Renaldisease;MyocardiAcutemyelogenousleukemia;SolidCancer;Thalassemia;Gout;FamilialmediterraneanBacterialinfection;Bacterial skinDiabeticnephropathy;Microalbuminuria;HypAsthma;ChronicobstructivepulmonaryCentral nervoussystemdisease;PolycystAsthma;Rheumatoidarthritis;PsoriaMigraineAcutelymphoblasticleukemia;UrinaryAlzheimersdisease;RestlesslegsTransplantrejection;Uveitis

Basal cellcarcinoma;ProstaticintraepithelialFamilialhypercholesterolemia;SitosteroleAlcoholism;Opiatedependence;IrritGeneralizedanxietydisorder;PanicHIV-1 infectionHIVinfection;Unclassified virusNon-alcoholicsteatohepatitis;Obesity;Non-Allergicrhinitis;ChronicobstructivepulmonaryAngina;Pulmonaryhypertension;ProstateAllergicconjunctivitis;Urticaria;Seasona